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Ketamine is an uncommon drug and people are feared, injured, robbed, or touched – all because they are unaware of the “dissociative” aspect of ketamine. Even though K only lasts between 15-40 minutes, it separates the mind from the body so you can’t feel safe or in control of your body. It’s impossible to walk, run, or even move – all of these can be dangerous if you suddenly find yourself in a difficult situation. There’s some specific information you should know about K, even if you think you know it all because you’ve always used K – here are some tips to help stay safe and get the most out of your K experience. Read these tips for safer K-travel. (Other articles on the effects of K as a drug, its history, drug culture, etc. will be coming soon, stay tuned on our page)

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Ketamine is used to induce general anesthesia in many species and as a constant rate infusion to provide analgesia and decrease the amount of inhalant used to maintain a surgical plane of anesthesia. It has been used intranasally in combination with midazolam in cats to induce sedation.2 Ketamine can inhibit NMDA receptors in the CNS and can decrease the wind-up pain effect. There is increasing interest in using it to prevent exaggerated pain associated with surgery or chronic pain states in animals.

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Ketamine is a rapid-acting general anesthetic that has significant analgesic activity and a relative lack of cardiopulmonary depressant effects in healthy animals. It is thought to induce both anesthesia and amnesia by functionally disrupting the CNS through over-stimulating the CNS or inducing a cataleptic state. Ketamine binds the phencyclidine-binding site of the NMDA receptors, which prevents glutamate, an excitatory neurotransmitter, from stimulating these receptors.