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MXE was designed in part in an attempt to avoid the urotoxicity associated with ketamine abuse; it was thought the compound’s increased potency and reduced dose would limit the accumulation of urotoxic metabolites in the bladder. Like ketamine, MXE has been found to produce bladder inflammation and fibrosis after the high dose, chronic administration in mice (although the dosages used were quite large). Reports of urotoxicity in humans have yet to appear in the medical literature. MXE for sale online.

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Buy Methoxetamine Online

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Methoxetamine, abbreviated as MXE, is a dissociative hallucinogen that has been sold as a designer drug. It differs from many dissociatives such as ketamine and phencyclidine (PCP) that were developed as pharmaceutical drugs for use as general anesthetics in that it was designed for grey market distribution. Buy Methoxetamine Online

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MXE is an arylcyclohexylamine. It acts mainly as an NMDA receptor antagonist, similar to other arylcyclohexylamines like ketamine and PCP. MXE for sale online

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Effects of MXE

MXE is reported to have a similar effect to ketamine. It was often believed to possess opioid properties due to its structural similarity to 3-HO-PCP, but this assumption is not supported by data, which shows an insignificant affinity for the µ-opioid receptor by the compound.

Recreational use of MXE has been associated with hospitalizations from high and/or combined consumption in the US and UK. Acute reversible cerebellar toxicity has been documented in three cases of hospital admission due to MXE overdose, lasting between one and four days after exposure.